Pilot/Technologies Recipient: Dr. Xuebiao Yao
Xuebiao Yao, PhD
Professor, Department of Physiology
Morehouse School of Medicine (MSM)
Supported Research
- Multi-color Quantum Dot Imaging for Predicting Breast Cancer Outcome and Designing Personalized Medicine
- Chemical Biological Study of BubR1 Signaling Pathway in Mitosis
ACTSI Support
- Funding: Pilot Grants and Research Technologies pilot project recipient
- Equipment:
- Deconvolution Microscope to enhance the existing molecular imaging capabilities at MSM (TTR new technologies equipment recipient - $320,000)-Located at MSM; and
- Carl Zeiss Palm System for the visualization of single molecules (TTR new technologies equipment recipient-only two others in the U.S. - $225,811) Co-funded by MSM R-CENTER-Located at MSM
Publication Selections
Cancer Cell | CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3
Dr. Yao works on chromosomal segregation during cell division and what goes wrong during tumorigenesis. With new agent development support from the ACTSI and co-funding from the MSM RCMI G20 grant, Dr. Yao, along with his collaborative team at Emory and MSM, have identified new microtuble and signal transduction pathways as drug targets.
EMBO Reports | TIP150 interacts with and targets MCAK to the microtubule plus-ends
The Journal of Biological Chemistry | Phospho-regulated ACAP4-ezrin interaction is essential for histamine-stimulated parietal cell secretion