Georgia Clinical & Translational Science Alliance

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Immune Modulator Drugs Improved Survival for People Hospitalized with COVID-19

Jun 9, 2022

COVID-19 molecules — Image Credit: Fernando Da Cunha/Science Photo Library

Preliminary results from ACTIV-1 Immune Modulator clinical trial show immune modulator drugs, infliximab and abatacept, substantially improved clinical status and reduced deaths in adults hospitalized with COVID-19. NIH launched this trial to evaluate safety and efficacy of three immune modulator drugs. The trial was coordinated and overseen by NCATS. NCATS’ CTSA Program and Trial Innovation Network played a key role in enrolling participants.